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Semen, which contains prostaglandins and other molecules that should not be placed directly into the uterine cavity, can be inadvertently inserted during IUI if the sample was not thoroughly washed. While frozen sperm can last a very long time, some believe its integrity may be compromised after thawing. Intra-uterine insemination IUI outcome is enhanced by shorter intervals from semen collection to sperm wash, from sperm wash to IUI time, and from semen collection to IUI time. Following gonadotropin therapy, OHSS usually develops several days after oocyte retrieval or assisted ovulation. Among the 38 patient and semen variables analyzed, only 3 were associated with successful IUI outcome: If two IUIs are scheduled, they are usually spaced at least 12 hours apart between 24 and 48 hours after the hCG. Conclusion This study demonstrated that sperm parameters are negatively affected from prolonged incubation time.
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This critical evaluation and the classification of substances are the result of an extensive discussion process by the members of the Commission, proceeding from a draft documentation prepared by members of the Commission, by ad hoc experts, or by the Scientific Secretariat of the Commission. Results from tests with different aquatic species from different trophic levels are available for the acute toxicity of resorcinol to aquatic organisms. Further, due to the lack of comparative toxicokinetic and toxicodynamic data between animals and humans for this end-point, it is not possible to extrapolate from animal studies to humans. Observers may participate in Board discussions only at the invitation of the Chairperson, and they may not participate in the final decision-making process.
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